Pancreatic Enzyme Replacement Therapy
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چکیده
Patients with chronic pancreatic insufficiency develop improper digestion due to the lack of digestive pancreatic enzymes. Such patients might complain of diarrhea and multi-nutrient deficiencies. Children with cystic fibrosis are at an increased risk of developing pancreatic insufficiency, while adults can develop chronic pancreatitis due to gallbladder disease or alcohol consumption. Regardless of the etiology, these patients might develop exocrine pancreatic deficiency and are at risk of developing malabsorption. Pancreatic enzyme replacement therapy is indicated in patients with malabsorption due to exocrine pancreatic insufficiency.
منابع مشابه
Symptomatic increase in intracranial pressure following pancreatic enzyme replacement therapy for cystic fibrosis.
A newly diagnosed 5-month-old infant with cystic fibrosis (CF) developed signs and symptoms of increased intracranial pressure (ICP) within days of starting pancreatic enzyme replacement therapy. Symptoms promptly resolved on two occasions after stopping enzyme replacement. At 10 months of age, enzyme replacement was well tolerated.
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